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The Coach House
Pipers Lane
Harpenden AL5 1AJ



We believe in skin improvement and the most natural results. Nucleofill is a relatively new bio-stimulator for skin rejuvenation and protection. As an anti-ageing treatment, it is designed to help cells retain water, improve skin elasticity and tightness, and aid in the prevention of wrinkles. Nucleofill offers various products for specific concerns and, as well as skin regeneration, there are also options for the neck and eyes.

The first course of action is to stimulate the fibroblasts in the skin, transforming them into myofibroblasts. Next, the production of your collagen and elastin is motivated, ultimately causing the skin to lift, tighten and thicken.



Nucleofill is a treatment for deep renewal and bio-restructure of the skin. This innovative treatment works on three levels: Lifting, antioxidation and hydration. It is unique and triple action at the cellular level, which gives the effect of visible and long-lasting rejuvenation.

Compatible to Profhilo it is a great all round skin booster and labelled as giving you a ‘second skin’. It can be used on all areas of the face meaning it can help with dark circles and fine lines around the eyes too. Nucleofill is an innovative biotechnology in aesthetic medicine and anti-aging treatments. This scientifically proven method of skin biostimulation contains polynucleotides that stimulate the skin to rebuild in a three-way mechanism.

The first course of action is stimulation of the receptors on fibroblasts in the skin. Due to such stimulation, they transform into myofibroblasts. The process of the production of type I collagen and elastin is stimulated, which causes the skin to thicken and lift. The second mechanism is the removal of free radicals and antioxidant activity. Polynucetides bind water and ensure long-term iso-osmotic hydration of the extracellular matrix, as a result, the skin becomes moisturized and firm.

Prices Starting From


The Treatment

At a Glance

From 30 Minutes
Visible After 2 Sessions, 4 Weeks Apart
Suitable For
Dehydrated/Dull Skin, Fine Lines/Wrinkles, Sagging Skin
Harpenden Skin Clinic - FAQ's

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You May Have

Does Nucleofill hurt?

People report some discomfort as the treatment takes place; however, this depends on the area being treated and individual differences in pain tolerance. Numbing cream is applied before the injections are given to reduce discomfort.

How many treatments will I need?

This depends on the severity of the fine lines and the area being treated. In most cases, two treatments are recommended at least one month apart. To maintain the results, patients may elect to repeat the treatment at 6-12 month intervals.

Are there any side effects?

Redness, swelling, itchiness and tenderness at the injection sites can occur, but the effects should subside within the first 24 hours.

When will I see results?

Skin appears smoother and hydrated immediately. As collagen and elastin levels increase, fine lines are reduced. This takes time, meaning the full effect of the treatment will not be seen until a few weeks after the final treatment.

Harpenden Skin Clinic

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